SARS-CoV-2 Spike S2 Protein (P.1 - gamma) (His tag)

Produktnummer ABIN6992375

Produktdetails

Target: SARS-CoV-2 Spike S2

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: P.1 - gamma

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike S2 Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag

Sequenz: AA 686-1213

Produktmerkmale: SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T1027I/ V1176F mutations were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Antigendetails

Target: SARS-CoV-2 Spike S2

Andere Bezeichnung: SARS-CoV-2 S2 protein (SARS-CoV-2 Spike S2 Produkte)

Synonyme: E2 Protein, Surface Glycoprotein Protein, S Protein

Substanzklasse: Viral Protein

Hintergrund: The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.

Molekulargewicht: 59.9 kDa