ROR2 Protein (His-Avi Tag,Biotin)

Produktnummer ABIN7275535

Produktdetails

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ROR2 Protein ist gelabelt mit His-Avi Tag,Biotin.

Sequenz: Val34-Gly403

Reinheit: > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-ROR2 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human ROR2, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Andere Bezeichnung: ROR2 (ROR2 Produkte)

Synonyme: BDB Protein, BDB1 Protein, NTRKR2 Protein, Ntrkr2 Protein, mRor2 Protein, ROR2 Protein, bdb Protein, bdb1 Protein, Xror2 Protein, ntrkr2 Protein, MGC97773 Protein, LOC100219935 Protein, ror2 Protein, xror2 Protein, receptor tyrosine kinase like orphan receptor 2 Protein, receptor tyrosine kinase-like orphan receptor 2 Protein, receptor tyrosine kinase like orphan receptor 2 L homeolog Protein, ROR2 Protein, Ror2 Protein, ror2 Protein, ror2.L Protein

Hintergrund: BDB, BDB1, NTRKR2, ROR2,ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.

Molekulargewicht: 44.2 kDa. Due to glycosylation, the protein migrates to 54-65 kDa based on Tris-Bis PAGE result.

UniProt: A1L4F5

Pathways: RTK Signalweg, WNT Signalweg