PGLYRP1 Protein (AA 19-182) (Fc Tag)
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- Target Alle PGLYRP1 Proteine anzeigen
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 19-182
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PGLYRP1 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Mouse PGLYRP1 Protein
- Sequenz
- Phe19-Glu182
- Produktmerkmale
- Recombinant Mouse PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Glu182.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS, 10 % Glycerol ( pH 8.0).
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- Andere Bezeichnung
- PGLYRP1 (PGLYRP1 Produkte)
- Synonyme
- PGLYRP1 Protein, PGLYRP Protein, pgrp Protein, tag7 Protein, pgrps Protein, pglyrp Protein, pgrp-s Protein, tnfsf3l Protein, MGC108330 Protein, MGC108469 Protein, PGRP-SC1a Protein, si:dkey-113g17.4 Protein, si:ch211-202c21.3 Protein, PGRP Protein, PGRP-S Protein, PGRPS Protein, TAG7 Protein, TNFSF3L Protein, Pglyrp Protein, Tag7 Protein, Tasg7 Protein, Tnfsf3l Protein, Pgrp Protein, peptidoglycan recognition protein 1 Protein, peptidoglycan recognition protein 1 L homeolog Protein, peptidoglycan recognition protein 5 Protein, PGLYRP1 Protein, pglyrp1.L Protein, pglyrp1 Protein, pglyrp5 Protein, Pglyrp1 Protein
- Hintergrund
- Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
- Molekulargewicht
- 45.7 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
- UniProt
- O88593
- Pathways
- Activation of Innate immune Response
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