IL13 Receptor alpha 1 Protein (AA 27-343) (Fc Tag)
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- Target Alle IL13 Receptor alpha 1 (IL13RA1) Proteine anzeigen
- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 27-343
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL13 Receptor alpha 1 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human IL-13Ra1 Protein
- Sequenz
- Ala27-Thr343
- Produktmerkmale
- Recombinant Human IL-13Ra1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala27-Thr343.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-13 at 1μg/ml (100μl/Well). Dose response curve for Human IL-13Ra1, hFc Tag with the EC50 of 2.7μg/ml determined by ELISA. The affinity constant of 53.1nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
- Andere Bezeichnung
- IL-13Ra1 (IL13RA1 Produkte)
- Synonyme
- CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213A1 Protein, IL-13Ra Protein, NR4 Protein, AI882074 Protein, CD213a1 Protein, IL-13r[a] Protein, Il13ra Protein, IL13RA1 Protein, il-13ra1 Protein, si:ch211-150g2.2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 1 Protein, interleukin 13 receptor, alpha 1 Protein, interleukin 13 receptor, alpha 1-like Protein, IL13RA2 Protein, IL13RA1 Protein, Il13ra1 Protein, il13ra1 Protein, LOC100360218 Protein
- Hintergrund
- Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
- Molekulargewicht
- 63.4 kDa. Due to glycosylation, the protein migrates to 78-90 kDa based on Tris-Bis PAGE result.
- UniProt
- P78552
- Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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