IL3RA Protein (AA 19-305) (Fc Tag)
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- Target Alle IL3RA Proteine anzeigen
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 19-305
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL3RA Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human IL-3 R alpha/CD123 Protein
- Sequenz
- Thr19-Arg305
- Produktmerkmale
- Recombinant Human IL-3 R alpha/CD123 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr19-Arg305.
- Reinheit
- > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-3, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-3 R alpha, hFc Tag with the EC50 of 42.7ng/ml determined by ELISA. See testing image for detail.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Andere Bezeichnung
- IL-3 R alpha (IL3RA Produkte)
- Synonyme
- CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
- Hintergrund
- Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
- Molekulargewicht
- 59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signalweg
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