IL3RA Protein (Fc-His Tag)
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- Target Alle IL3RA Proteine anzeigen
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL3RA Protein ist gelabelt mit Fc-His Tag.
- Applikation
- ELISA
- Verwendungszweck
- Recombinant human CD123 protein with C-terminal human Fc and 6xHis tag
- Spezifität
- CD123 (Thr19-Arg305) hFc (Glu99-Ala330) 6xHis tag
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- affinity purification
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL3RA Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Konservierungsmittel
- Without preservative
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Andere Bezeichnung
- CD123 (IL3RA Produkte)
- Synonyme
- CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
- Hintergrund
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Synonymes: IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
Description: Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells - Molekulargewicht
- predicted molecular mass of 80-90 kDa after removal of the signal peptide.
- Gen-ID
- 3563
- UniProt
- P26951
- Pathways
- JAK-STAT Signalweg
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