Hepcidin Protein (AA 60-84) (GST tag)

Produktnummer ABIN7274792

Produktdetails

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 60-84

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Hepcidin Protein ist gelabelt mit GST tag.

Verwendungszweck: Human Hepcidin/HAMP Protein

Sequenz: Asp60-Thr84

Produktmerkmale: Recombinant Human Hepcidin/HAMP Protein is expressed from E.coli with GST tag at the N-Terminus.It contains Asp60-Thr84.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: Hepcidin (HAMP Produkte)

Synonyme: HEPC Protein, HFE2B Protein, LEAP1 Protein, PLTR Protein, Hepcidin Protein, Hamp1 Protein, Hepc Protein, Hepc1 Protein, HAMP Protein, hepcidin Protein, hamp1 Protein, hep1 Protein, hepcidin antimicrobial peptide Protein, hepcidin-like Protein, hepcidin-1 Protein, Ham percentage Protein, HAMP Protein, Hamp Protein, hamp Protein, LOC100135935 Protein, LOC106584587 Protein

Hintergrund: Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Molekulargewicht: 29.08 kDa same as Tris-Bis PAGE result.

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis