Poliovirus Receptor Protein (PVR) (AA 21-343) (His-Avi Tag)
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- Target Alle Poliovirus Receptor (PVR) Proteine anzeigen
- Poliovirus Receptor (PVR)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 21-343
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Poliovirus Receptor Protein ist gelabelt mit His-Avi Tag.
- Verwendungszweck
- Human CD155/PVR Protein
- Sequenz
- Trp21-Asn343
- Produktmerkmale
- Recombinant Human CD155/PVR Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Trp21-Asn343.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD155, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 0.5μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product PVR Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Poliovirus Receptor (PVR)
- Andere Bezeichnung
- CD155 (PVR Produkte)
- Synonyme
- PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
- Hintergrund
- CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
- Molekulargewicht
- 38 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom
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