Poliovirus Receptor Protein (PVR) (mFc-His Tag)

Produktnummer ABIN6961100

Produktdetails

Target: Poliovirus Receptor (PVR)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Poliovirus Receptor Protein ist gelabelt mit mFc-His Tag.

Applikation: ELISA

Verwendungszweck: Recombinant human CD155 protein with C-terminal mouse Fc and 6xHis tag

Spezifität: CD155 (Trp21-Asn343) mFc (Pro99-Lys330) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Haltbarkeit: 12 months

Antigendetails

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: CD155 (PVR Produkte)

Synonyme: PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein

Hintergrund: Synonymes: PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
Description: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: predicted molecular mass of 62.2 kDa after removal of the signal peptide. The apparent molecular mass of CD155-mFc-His is 95-130 kDa due to glycosylation.

Gen-ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom