AXL Protein (AA 20-445) (His tag)
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- Target Alle AXL Proteine anzeigen
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-445
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses AXL Protein ist gelabelt mit His tag.
- Verwendungszweck
- Mouse AXL Protein
- Sequenz
- His20-Trp445
- Produktmerkmale
- Recombinant Mouse AXL Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His20-Trp445.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product AXL Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Andere Bezeichnung
- AXL (AXL Produkte)
- Synonyme
- JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein
- Hintergrund
- Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
- Molekulargewicht
- 47.8 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_033491
- Pathways
- RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
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