PRKAR1A Protein (His tag)

Produktnummer ABIN7318228

Produktdetails

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PRKAR1A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PRKAR1A Protein (His Tag)

Sequenz: Glu2-Val381

Produktmerkmale: Recombinant Human cAMP-dependent protein kinase regulatory type I-alpha is produced by our Mammalian expression system and the target gene encoding Glu2-Val381 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Andere Bezeichnung: PRKAR1A (PRKAR1A Produkte)

Synonyme: ACRDYS1 Protein, ADOHR Protein, CAR Protein, CNC Protein, CNC1 Protein, PKR1 Protein, PPNAD1 Protein, PRKAR1 Protein, TSE1 Protein, 1300018C22Rik Protein, RIalpha Protein, Tse-1 Protein, Tse1 Protein, RIIA Protein, prkar1a Protein, zgc:92515 Protein, im:7047729 Protein, cnc1 Protein, pkr1 Protein, ppnad1 Protein, prkar1 Protein, tse1 Protein, protein kinase cAMP-dependent type I regulatory subunit alpha Protein, protein kinase, cAMP dependent regulatory, type I, alpha Protein, protein kinase cAMP-dependent type 1 regulatory subunit alpha Protein, protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a Protein, cAMP-dependent protein kinase type I-alpha regulatory subunit pseudogene Protein, protein kinase cAMP-dependent type I regulatory subunit alpha S homeolog Protein, PRKAR1A Protein, Prkar1a Protein, prkar1aa Protein, LOC707275 Protein, prkar1a.S Protein

Hintergrund:

Background: cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.

Synonym: Tissue-specific extinguisher 1,TSE1

Molekulargewicht: 44.0 kDa

UniProt: P10644

Pathways: Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma