Prostate Specific Antigen Protein (PSA) (His tag)

Produktnummer ABIN7197538

Produktdetails

Target: Prostate Specific Antigen (PSA)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Prostate Specific Antigen Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PSA/KLK3 Protein (His Tag)(Active)

Sequenz: Met 1-Pro 261

Produktmerkmale: A DNA sequence encoding the human KLK3 (P07288) (Met 1-Pro 261) was fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to cleave the colorimetric peptide substrate, Succinyl-Arg-Pro-Tyr-p-Nitroanilide(Suc-RPY-pNA). The specific activity is >100 pmoles/min/μg.(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: PSA/KLK3 (PSA Produkte)

Synonyme: APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein

Hintergrund:

Background: KLK3(Kallikrein 3); also known as Prostate Specific Antigen (PSA); kallikrein-related peptidase 3; Gamma-seminoprotein; is a secreted protein of the glandular kallikrein subfamily of serine proteases.KLK3 contains one peptidase S1 domain.KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Synonym: APS;Hk3;KLK2A1;PSA;Prostate-Specific Antigen; PSA; Gamma-Seminoprotein; Seminin; Kallikrein-3; P-30 Antigen; Semenogelase;

Molekulargewicht: 28.3 kDa

UniProt: P07288

Pathways: Komplementsystem