Prostate Specific Antigen Protein (PSA) (Fc Tag)

Produktnummer ABIN6964284

Produktdetails

Target: Prostate Specific Antigen (PSA)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Prostate Specific Antigen Protein ist gelabelt mit Fc Tag.

Sequenz: KLK3(Ile25-Phe261)+hFc(Glu99-Ala330)

Produktmerkmale: Tagged Protein: C-Human Fc tag

Aufreinigung: affinity purification

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Haltbarkeit: 12 months

Antigendetails

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: KLK3 (PSA Produkte)

Synonyme: APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein

Hintergrund: Synonymes: APS, hK3, KLK2A1, PSA
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]

Molekulargewicht: 51.7 kDa

UniProt: P07288

Pathways: Komplementsystem