IGFBP5 Protein (His tag)

Produktnummer ABIN7318630

Produktdetails

Target: IGFBP5 (Insulin-Like Growth Factor Binding Protein 5 (IGFBP5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses IGFBP5 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human IGFBP-5/IGFBP5 Protein (His Tag)

Sequenz: Leu21-Glu272

Produktmerkmale: Recombinant Human Insulin-Like Growth Factor-Binding Protein 5 is produced by our Mammalian expression system and the target gene encoding Leu21-Glu272 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IGFBP5 (Insulin-Like Growth Factor Binding Protein 5 (IGFBP5))

Andere Bezeichnung: IGFBP-5/IGFBP5 (IGFBP5 Produkte)

Synonyme: IBP5 Protein, AI256729 Protein, AW208790 Protein, IGFBP-5 Protein, IGFBP-5P Protein, IGF-BP5 Protein, igfbp5 Protein, ibp5 Protein, IBP-5 Protein, xIGFBP-5 Protein, IGFBP5 Protein, igfbp5b Protein, zgc:165472 Protein, insulin like growth factor binding protein 5 Protein, insulin-like growth factor binding protein 5 Protein, insulin like growth factor binding protein 5 L homeolog Protein, insulin-like growth factor binding protein 5b Protein, insulin-like growth factor-binding protein 5 Protein, insulin-like growth factor binding protein 5a Protein, IGFBP5 Protein, Igfbp5 Protein, igfbp5.L Protein, igfbp5b Protein, igfbp5 Protein, LOC100194500 Protein, igfbp5a Protein

Hintergrund:

Background: Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. They have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP-5 contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP-5 is expressed by fibroblasts, myoblasts and Osteosarcoma. It is also present at lower levels in liver, kidney, and brain.

Synonym: Insulin-Like Growth Factor-Binding Protein 5, IBP-5, IGF-Binding Protein 5, IGFBP-5, IGFBP5, IBP5

Molekulargewicht: 29.6 kDa

UniProt: P24593

Pathways: WNT Signalweg, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Growth Factor Binding