IDO1 Protein (His tag)
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- Target Alle IDO1 Proteine anzeigen
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses IDO1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse IDO1/IDO Protein (His Tag)
- Sequenz
- Met1-Pro407
- Produktmerkmale
- Recombinant Mouse Indoleamine 2,3-dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Pro407 is expressed with a 6His tag at the N-terminus.
- Reinheit
- > 95 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IDO1 Protein
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Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (His tag)
IDO1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (GST tag)IDO1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) protein (GST tag)IDO1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) proteinIDO1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (Strep Tag)Crystallography grade IDO1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-407) protein (Strep Tag)Crystallography grade IDO1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) protein (Myc-DYKDDDDK Tag)IDO1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Sodium Acetate, 150 mM NaCl and 20 % Glycerol, pH 4.5.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- Andere Bezeichnung
- IDO1/IDO (IDO1 Produkte)
- Synonyme
- INDO Protein, ido Protein, indo Protein, IDO Protein, cd107b Protein, IDO1 Protein, IDO-1 Protein, Ido Protein, Indo Protein, indoleamine 2,3-dioxygenase 1 Protein, indoleamine 2,3-dioxygenase 1 L homeolog Protein, indoleamine 2,3-dioxygenase 1-like Protein, IDO1 Protein, ido1.L Protein, ido1 Protein, Ido1 Protein, LOC100050681 Protein
- Hintergrund
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Background: Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.
Synonym: Indole 2,3-dioxygenase, Indoleamine 2,3-dioxygenase 1, IDO-1, IDO1, IDO, INDO
- Molekulargewicht
- 47.1 kDa
- UniProt
- P28776
- Pathways
- Activated T Cell Proliferation
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