IDO1 Protein (AA 1-407) (His tag)
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- Target Alle IDO1 Proteine anzeigen
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 1-407
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses IDO1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Maus
- Produktmerkmale
- Mouse IDO (aa 1-407) is fused at the C-terminus to a His-tag.
- Reinheit
- >90 % (SDS-PAGE)
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- <1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IDO1 Protein
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Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (His tag)
IDO1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (GST tag)IDO1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) protein (His tag)IDO1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) protein (GST tag)IDO1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) proteinIDO1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) protein (Strep Tag)Crystallography grade IDO1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-407) protein (Strep Tag)Crystallography grade IDO1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Indoleamine 2,3-Dioxygenase 1 (IDO1) (Active) protein (Myc-DYKDDDDK Tag)IDO1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Specific Activity: >100'000U/mg protein with L-tryptophan as substrate and after addition of 7μM hemin for protein induction. One unit is defined as the amount of enzyme that produces 1nmol of kynurenine per hour.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in 50 mM TRIS-Cl, pH 7.4, containing 1 mM EDTA.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Haltbarkeit
- 3 months
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- Target
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
- Andere Bezeichnung
- IDO (IDO1 Produkte)
- Synonyme
- INDO Protein, ido Protein, indo Protein, IDO Protein, cd107b Protein, IDO1 Protein, IDO-1 Protein, Ido Protein, Indo Protein, indoleamine 2,3-dioxygenase 1 Protein, indoleamine 2,3-dioxygenase 1 L homeolog Protein, indoleamine 2,3-dioxygenase 1-like Protein, IDO1 Protein, ido1.L Protein, ido1 Protein, Ido1 Protein, LOC100050681 Protein
- Hintergrund
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
- Molekulargewicht
- ~40kDa (SDS-PAGE)
- UniProt
- P28776
- Pathways
- Activated T Cell Proliferation
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