GADD45G Protein (His tag)

Produktnummer ABIN7318513

Produktdetails

Target: GADD45G (Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GADD45G Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GADD45γ/GADD45G Protein (His Tag)

Sequenz: Met 1-Glu159

Produktmerkmale: Recombinant Human Growth Arrest and DNA Damage-Inducible Protein GADD45 gamma is produced by our E.coli expression system and the target gene encoding Met1-Glu159 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: GADD45G (Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G))

Andere Bezeichnung: GADD45gamma/GADD45G (GADD45G Produkte)

Synonyme: zgc:77806 Protein, GADD45G Protein, XGadd45-gamma Protein, cr6 Protein, ddit2 Protein, gadd45gamma Protein, grp17 Protein, xgadd45g Protein, AI327420 Protein, C86281 Protein, CR6 Protein, DDIT2 Protein, OIG37 Protein, GADD45gamma Protein, GRP17 Protein, growth arrest and DNA-damage-inducible, gamma a Protein, growth arrest and DNA damage inducible gamma Protein, growth arrest and DNA-damage-inducible 45 gamma Protein, growth arrest and DNA-damage-inducible, gamma Protein, gadd45ga Protein, GADD45G Protein, gadd45g Protein, Gadd45g Protein

Hintergrund:

Background: Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apoptosis. GADD45G inhibits cell growth and differentiation by androgens. The mRNA expression is down-regulated in hepatocellular carcinoma.

Synonym: Growth Arrest and DNA Damage-Inducible Protein GADD45 Gamma, Cytokine-Responsive Protein CR6, DNA Damage-Inducible Transcript 2 Protein, DDIT-2, GADD45G, CR6, DDIT2

Molekulargewicht: 19.3 kDa

UniProt: O95257

Pathways: Zellzyklus