GADD45G Protein (AA 1-159) (His tag)

Produktnummer ABIN1096795

Produktdetails

Target: GADD45G (Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-159

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GADD45G Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GADD45γ/GADD45G (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGDVQR LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE

Produktmerkmale: Recombinant Human Growth Arrest and DNA Damage-Inducible Protein GADD45gamma/GADD45G is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Glu159) of Human GADD45G fused with a 6His tag at the N-terminus. and a 6His at the C-terminus

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: GADD45G (Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G))

Andere Bezeichnung: GADD45G (GADD45G Produkte)

Synonyme: zgc:77806 Protein, GADD45G Protein, XGadd45-gamma Protein, cr6 Protein, ddit2 Protein, gadd45gamma Protein, grp17 Protein, xgadd45g Protein, AI327420 Protein, C86281 Protein, CR6 Protein, DDIT2 Protein, OIG37 Protein, GADD45gamma Protein, GRP17 Protein, growth arrest and DNA-damage-inducible, gamma a Protein, growth arrest and DNA damage inducible gamma Protein, growth arrest and DNA-damage-inducible 45 gamma Protein, growth arrest and DNA-damage-inducible, gamma Protein, gadd45ga Protein, GADD45G Protein, gadd45g Protein, Gadd45g Protein

Sub Type: Fusionprotein

Hintergrund: Growth Arrest and DNA Damage-Inducible Protein GADD45 Ypsilon (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apoptosis. GADD45G inhibits cell growth and differentiation by androgens. The mRNA expression is down-regulated in hepatocellular carcinoma.
Alternative Names: Growth Arrest and DNA Damage-Inducible Protein GADD45 Gamma, Cytokine-Responsive Protein CR6, DNA Damage-Inducible Transcript 2 Protein, DDIT-2, GADD45G, CR6, DDIT2

Molekulargewicht: 19.28kDa

UniProt: O95257

Pathways: Zellzyklus