COL4a3 Protein (Fc Tag)

Produktnummer ABIN7321080

Produktdetails

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses COL4a3 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Rat COL4A3 Protein (Fc Tag)

Sequenz: Gly1426-His1670

Produktmerkmale: A DNA sequence encoding the rat COL4A3 (NP_001129231) (Gly1426-His1670) was expressed with Fc region of human IgG1 at the N-terminus.

Reinheit: > 85 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Andere Bezeichnung: COL4A3 (COL4A3 Produkte)

Synonyme: zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein

Hintergrund:

Background: COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.

Synonym: COL4A3

Molekulargewicht: 55.2 kDa

NCBI Accession: NP_001129231

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity