COL4a3 Protein (AA 1446-1667, partial) (His tag)

Produktnummer ABIN5709311

Produktdetails

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1446-1667, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses COL4a3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: GLKGKRGDSG SPATWTTRGF VFTRHSQTTA IPSCPEGTVP LYSGFSFLFV QGNQRAHGQD LGTLGSCLQR FTTMPFLFCN VNDVCNFASR NDYSYWLSTP ALMPMNMAPI TGRALEPYIS RCTVCEGPAI AIAVHSQTTD IPPCPHGWIS LWKGFSFIMF TSAGSEGTGQ ALASPGSCLE EFRASPFLEC HGRGTCNYYS NSYSFWLASL NPERMFRKPI PSTVKAGELE KIISRCQVCM KK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Andere Bezeichnung: CO4A3 (COL4A3 Produkte)

Synonyme: zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein

Hintergrund: Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity, these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms.

Molekulargewicht: 30.6 kDa

UniProt: Q01955

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity