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COL4a3 Produkte

(Collagen, Type IV, alpha 3 (COL4A3))
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010].

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Ausgewählte COL4a3 Kategorien

COL4a3 Antikörper

High quality antibodies with extensive validation data.

COL4a3 ELISA Kits

Reliable ELISA kits for a wide range of species.

COL4a3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene COL4a3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7434707
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse, Rat
Applikation ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN678128
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
Kat. Nr. ABIN7266460
Menge 100 μL
Datenblatt Datenblatt

Empfohlene COL4a3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954946
Menge 96 tests
Datenblatt Datenblatt

Empfohlene COL4a3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7321080
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395947
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5709311
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren COL4a3 Produkten

Sun, Liu, Pei, Yao, Ma, Mu, Wang, Zhang, Yang, Wang, Xue, Zhai, Carare, Qin, Yan: "The impairment of intramural periarterial drainage in brain after subarachnoid hemorrhage." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 187, (2022) (PubMed).

Yasuda, Fukui, Okada, Yamawaki: "T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 11, pp. 1135-1144, (2017) (PubMed).

Jeruschke, Jeruschke, DiStasio, Karaterzi, Büscher, Nalbant, Klein-Hitpass, Hoyer, Weiss, Stottmann, Weber: "Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137043, (2015) (PubMed).

Faiz, Tjin, Harkness, Weckmann, Bao, Black, Oliver, Burgess: "The expression and activity of cathepsins D, H and K in asthmatic airways." in: PLoS ONE, Vol. 8, Issue 3, pp. e57245, (2013) (PubMed).

Thevenard, Ramont, Mir, Dupont-Deshorgue, Maquart, Monboisse, Brassart-Pasco: "A new anti-tumor strategy based on in vivo tumstatin overexpression after plasmid electrotransfer in muscle." in: Biochemical and biophysical research communications, Vol. 432, Issue 4, pp. 549-52, (2013) (PubMed).

Jones, Wang, Dookie, Griffin: "The role of TG2 in ECV304-related vasculogenic mimicry." in: Amino acids, Vol. 44, Issue 1, pp. 89-101, (2013) (PubMed).

Tan, ONeill, Naciri, Dowling, Al-Rubeai: "Cellular and transcriptomic analysis of human mesenchymal stem cell response to plasma-activated hydroxyapatite coating." in: Acta biomaterialia, Vol. 8, Issue 4, pp. 1627-38, (2012) (PubMed).

Arcaro, Volinia, Zvelebil, Stein, Watton, Layton, Gout, Ahmadi, Downward, Waterfield: "Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity." in: The Journal of biological chemistry, Vol. 273, Issue 49, pp. 33082-90, (1999) (PubMed).

Synonyme und alternative Namen zu COL4a3

collagen type IV alpha 3 chain (COL4A3), collagen, type IV, alpha 3 (col4a3), collagen, type IV, alpha 3 (Col4a3), collagen type IV alpha 3 chain (Col4a3), alpha3(IV), zTumstatin, [a]3(IV)

Bezeichner auf Proteinebene für COL4a3

  • type IV collagen alpha 3 chain
  • collagen alpha-3(IV) chain
  • collagen type IV alpha3 chain
  • procollagen, type IV, alpha 3
  • tumstatin
  • collagen, type IV, alpha 3 (Goodpasture antigen)
  • collagen IV, alpha-3 polypeptide
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