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COL6a3 Produkte

(Collagen, Type VI, alpha 3 (COL6a3))
This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009].

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Ausgewählte COL6a3 Kategorien

COL6a3 Antikörper

High quality antibodies with extensive validation data.

COL6a3 ELISA Kits

Reliable ELISA kits for a wide range of species.

COL6a3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene COL6a3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7183368
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation IF, IHC, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN1534348
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
Kat. Nr. ABIN7186377
Menge 100 μg
Datenblatt Datenblatt

Empfohlene COL6a3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6954957
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962139
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951494
Menge 96 tests
Datenblatt Datenblatt

Empfohlene COL6a3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7195175
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7195176
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7080512
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren COL6a3 Produkten

James, Hurley, Gamage, Zhang, Vather, Pantham, Murthi, Chamley: "Isolation and characterisation of a novel trophoblast side-population from first trimester placentae." in: Reproduction (Cambridge, England), Vol. 150, Issue 5, pp. 449-62, (2015) (PubMed).

Kang, Wang, Axell-House, Soni, Chu, Chipitsyna, Sarosiek, Sendecki, Hyslop, Al-Zoubi, Yeo, Arafat: "Clinical significance of serum COL6A3 in pancreatic ductal adenocarcinoma." in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, Vol. 18, Issue 1, pp. 7-15, (2014) (PubMed).

McCulloch, Rawling, Sjöholm, Franck, Dankel, Price, Knight, Liversedge, Mellgren, Nystrom, Carlsson, Kos: "COL6A3 is regulated by leptin in human adipose tissue and reduced in obesity." in: Endocrinology, Vol. 156, Issue 1, pp. 134-46, (2014) (PubMed).

Synonyme und alternative Namen zu COL6a3

collagen type VI alpha 3 chain (COL6A3), collagen, type VI, alpha 3 (col6a3), collagen, type VI, alpha 3 (Col6a3), collagen type VI alpha 3 chain (Col6a3), AI507288, Col6a-3, COL6A3, wu:fb06e12, wu:fs74g09

Bezeichner auf Proteinebene für COL6a3

  • collagen alpha-3(VI) chain
  • type VI collagen alpha 3 chain
  • alpha 3 type VI collagen
  • collagen, type VI, alpha 3
  • collagen alpha-3(VI) chain-like
  • collagen alpha 3 chain type VI
  • collagen alpha3(VI)
  • procollagen, type VI, alpha 3
  • type VI collagen alpha 3 subunit
  • collagen VI, alpha-3 polypeptide
  • alpha-3 collagen type VI
  • collagen type VI alpha 3
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