Cathepsin L Protein (AA 18-334) (His tag)

Produktnummer ABIN7320749

Produktdetails

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 18-334

Spezies: Maus

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Cathepsin L Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Cathepsin L/CTSL Protein (aa 18-334, His Tag)

Sequenz: Thr18-Asn334

Produktmerkmale: Recombinant Mouse Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Asn334 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L/CTSL (CTSL1 Produkte)

Synonyme: CATL Protein, CTSL1 Protein, MEP Protein, 1190035F06Rik Protein, Ctsl1 Protein, fs Protein, nkt Protein, CATHL Protein, CatL Protein, Ctsl Protein, CTSL Protein, mep Protein, catl Protein, ctsl Protein, cpl-1 Protein, MGC80629 Protein, MGC107932 Protein, LOC663234 Protein, 26-29-p Protein, Cp1 Protein, si:dkey-121a11.6 Protein, CTSV Protein, catL Protein, cb15 Protein, ctsl1b Protein, hgg1 Protein, wu:fb30g09 Protein, zgc:92089 Protein, cathepsin L Protein, cathepsin V Protein, cathepsin L L homeolog Protein, cathepsin L1 Protein, Cathepsin L1 Protein, Cathepsin L Protein, testin gene Protein, cathepsin 12 Protein, cathepsin Lb Protein, cathepsin L.1 Protein, CTSL Protein, Ctsl Protein, CTSV Protein, ctsl.L Protein, ctsl Protein, LOC100008830 Protein, catl1 Protein, 26-29-p Protein, catl Protein, Tsp_11596 Protein, Testin Protein, cts12 Protein, LOC102156614 Protein, ctslb Protein, ctsl.1 Protein

Hintergrund:

Background: Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

Synonym: Cathepsin L1, Major excreted protein, p39 cysteine proteinase, Ctsl1,1190035F06Rik

Molekulargewicht: 36.8 kDa

UniProt: P06797

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades