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Cathepsin L1 Produkte

(Cathepsin L1 (CTSL1))

Kategorien

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012].

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Ausgewählte Cathepsin L1 Kategorien

Cathepsin L1 Antikörper

High quality antibodies with extensive validation data.

Cathepsin L1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Cathepsin L1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Cathepsin L1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN7431587
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Pig, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN687532
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7239770
Menge 200 μL
Datenblatt Datenblatt

Empfohlene Cathepsin L1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6954461
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954463
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962834
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Cathepsin L1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122182
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350725
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350727
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Cathepsin L1 Produkten

Zhang, Wei, Li, He, Liu, Deng, Cheng, Du, Liu, Chen, Sun, Yu, Fu: "COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2." in: International journal of biological sciences, Vol. 18, Issue 6, pp. 2362-2371, (2022) (PubMed).

Yeow, Kotamraju, Wang, Chopra, Azme, Wu, Schoep, Delaney, Feindel, Li, Kennedy, Allen, Kennedy, Larma, Sampson, Mahakian, Fite, Zhang, Friman, Mann, Aziz, Kumarasinghe, Johansson, Ee, Yeoh, Mou et al.: "Immune-mediated ECM depletion improves tumour perfusion and payload delivery. ..." in: EMBO molecular medicine, Vol. 11, Issue 12, pp. e10923, (2020) (PubMed).

Hernáez, Guerra, Salas, Andrés: "African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes." in: PLoS pathogens, Vol. 12, Issue 4, pp. e1005595, (2016) (PubMed).

Sudhan, Pampo, Rice, Siemann: "Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model." in: International journal of cancer, Vol. 138, Issue 11, pp. 2665-77, (2016) (PubMed).

Liu, Xu, Ye, Liang, Wu, Zheng, Deng, Li, Liu: "Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells." in: American journal of physiology. Renal physiology, Vol. 308, Issue 6, pp. F639-49, (2015) (PubMed).

Tholen, Wolanski, Stolze, Chiabudini, Gajda, Bronsert, Stickeler, Rospert, Reinheckel: "Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression." in: The Journal of biological chemistry, Vol. 290, Issue 25, pp. 15758-69, (2015) (PubMed).

Kim, Woo, Kim, Jang, Hwang, Kwon, Choi, Kim, Cheng, Jin, Kim, Kim, Kim: "Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid artery." in: Atherosclerosis, Vol. 233, Issue 2, pp. 579-83, (2014) (PubMed).

Baldzizhar, Fedorchuk, Jha, Rathinam, Henegariu, Czyzyk: "Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes." in: The Journal of biological chemistry, Vol. 288, Issue 3, pp. 1612-9, (2013) (PubMed).

Capoccia, Jin, Kong, Peek, Fassan, Rugge, Mills: "The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation." in: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1475-91, (2013) (PubMed).

García, Kohen, Maldonado, Sierralta, Muñoz, Villarroel, Strauss, Devoto: "Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period." in: Fertility and sterility, Vol. 97, Issue 3, pp. 707-13.e1, (2012) (PubMed).

Synonyme und alternative Namen zu Cathepsin L1

cathepsin L (CTSL), cathepsin L (Ctsl), cathepsin V (CTSV), cathepsin L L homeolog (ctsl.L), cathepsin L (ctsl), cathepsin L1 (LOC100008830), Cathepsin L1 (catl1), cathepsin L (26-29-p), Cathepsin L (catl), cathepsin L1 (Tsp_11596), testin gene (Testin), cathepsin 12 (cts12), cathepsin L1 (LOC102156614), cathepsin Lb (ctslb), cathepsin L.1 (ctsl.1), 26-29-p, 1190035F06Rik, CATHL, CATL, CatL, catl, catL, cb15, Cp1, cpl-1, Ctsl, CTSL, ctsl, CTSL1, Ctsl1, ctsl1b, CTSV, fs, hgg1, LOC663234, MEP, mep, MGC80629, MGC107932, nkt, si:dkey-121a11.6, wu:fb30g09, zgc:92089

Bezeichner auf Proteinebene für Cathepsin L1

  • cathepsin L1
  • major excreted protein
  • Cat L
  • furless
  • nackt
  • p39 cysteine proteinase
  • CP-2
  • MEP
  • cathepsin L
  • cyclic protein 2
  • Cathepsin L1
  • cathepsin L1-like
  • 26-29kD-proteinase
  • cysteine proteinase-1
  • Cathepsin L
  • CMB-23
  • testin-2
  • cathepsin V
  • cathepsin L, 1 b
  • cathepsin L, b
  • cathepsin Lb
  • cstlb
  • hatching gland 1
  • hatching gland gene 1
  • cathepsin L.1
  • ctslc
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