Cathepsin B Produkte
(Cathepsin B (CTSB))
Kategorien
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte Cathepsin B Kategorien
Cathepsin B Antikörper
High quality antibodies with extensive validation data.
Cathepsin B ELISA Kits
Reliable ELISA kits for a wide range of species.
Cathepsin B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Cathepsin B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (8)
Kat. Nr.
ABIN3021176
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7146996
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN687412
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Cathepsin B ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962721
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974773
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954447
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Cathepsin B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350702
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350704
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN2752768
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Cathepsin B Produkten
: "Matrix metalloproteinase 2 (MMP-2) levels are increased in active acromegaly patients." in: Endocrine, Vol. 57, Issue 1, pp. 148-155, (2018) (PubMed).: "Characterization of Novel Piperidine-Based Inhibitor of Cathepsin B-Dependent Bacterial Toxins and Viruses." in: ACS infectious diseases, Vol. 4, Issue 8, pp. 1235-1245, (2018) (PubMed).
: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).
: "Cysteine protease cathepsin B mediates radiation-induced bystander effects." in: Nature, Vol. 547, Issue 7664, pp. 458-462, (2017) (PubMed).
: "Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-β-induced autophagy." in: Nature cell biology, Vol. 18, Issue 8, pp. 851-63, (2016) (PubMed).
: "Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells." in: American journal of physiology. Renal physiology, Vol. 308, Issue 6, pp. F639-49, (2015) (PubMed).
: "Cathepsin B in human myometrium and in uterine leiomyomas at various stages of tumour growth." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 185, pp. 140-4, (2015) (PubMed).
: "Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting." in: Scientific reports, Vol. 5, pp. 13476, (2015) (PubMed).
: "Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats." in: Neural regeneration research, Vol. 9, Issue 13, pp. 1288-96, (2014) (PubMed).
: "?-Interferon-inducible lysosomal thiol reductase (GILT) maintains phagosomal proteolysis in alternatively activated macrophages." in: The Journal of biological chemistry, Vol. 289, Issue 46, pp. 31891-904, (2014) (PubMed).
Synonyme und alternative Namen zu Cathepsin B
cathepsin B (CTSB), cathepsin B (Ctsb), cathepsin B S homeolog (ctsb.S), cathepsin B (LOC692390), APPS, apps, CB, CPSB, cpsb, CTSB, LOC692390Bezeichner auf Proteinebene für Cathepsin B
- APP secretase
- amyloid precursor protein secretase
- cathepsin B1
- cysteine protease
- RSG-2
- BCSB
- cathepsin B
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