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Catechol-O-Methyltransferase Produkte

(Catechol-O-Methyltransferase (COMT))

Kategorien

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].

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Ausgewählte Catechol-O-Methyltransferase Kategorien

Catechol-O-Methyltransferase Antikörper

High quality antibodies with extensive validation data.

Catechol-O-Methyltransferase ELISA Kits

Reliable ELISA kits for a wide range of species.

Catechol-O-Methyltransferase Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Catechol-O-Methyltransferase Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (6)
Kat. Nr. ABIN185682
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN2854980
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (5)
Kat. Nr. ABIN185328
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Catechol-O-Methyltransferase ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954432
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954433
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954434
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Catechol-O-Methyltransferase Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122177
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350032
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666744
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Catechol-O-Methyltransferase Produkten

Bai, Tang, Zou, Meng, Tu, Xia, Cheng, Zhang, Yang, Mu, Wang, Qin, Lv, Cao, Qin, Jiang, Chen: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).

Ikeda, Iijima, Shinoda, Iwamoto, Takeda: "Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase." in: Molecules (Basel, Switzerland), Vol. 22, Issue 8, (2018) (PubMed).

Karpeta, Warzecha, Jerzak, Ptak, Gregoraszczuk: "Activation of the enzymes of phase I (CYP2B1/2) and phase II (SULT1A and COMT) metabolism by 2,2',4,4'-tetrabromodiphenyl ether (BDE47) in the pig ovary." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 34, Issue 3, pp. 436-42, (2012) (PubMed).

Yang, Yao, Zhou, Yin, Zhang, Harris: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." in: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, (2012) (PubMed).

Hevir, Sinkovec, Rižner: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." in: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).

Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Stroth, Reinhardt, Thöne, Hille, Schneider, Härtel, Weidemann, Bös, Spitzer: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." in: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).

Lim, Kim, Kim, Park, Han, Han, Lee, Yang, Ryu: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).

Demetrovics, Varga, Szekely, Vereczkei, Csorba, Balazs, Hoffman, Sasvari-Szekely, Barta: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." in: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).

Bodenmann, Landolt: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." in: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).

Synonyme und alternative Namen zu Catechol-O-Methyltransferase

catechol-O-methyltransferase (COMT), catechol-O-methyltransferase (Comt), microRNA 4761 (MIR4761), catechol-O-methyltransferase (comt), catechol-O-methyltransferase (comt.2), catechol-O-methyltransferase S homeolog (comt.S), methyltransferase (Rv1703c), catechol-o-methyltransferase (Mb1729c), catechol-O-methyltransferase a (comta), catechol-O-methyltransferase b (comtb), catechol O-methyltransferase (LOC100354142), COMT, comt, Comt1, D16Wsu103e, D330014B15Rik, mb-comt, MGC154444, s-comt, si:dkey-13a21.15, zgc:114157, zgc:162236, zK13A21.15

Bezeichner auf Proteinebene für Catechol-O-Methyltransferase

  • catechol O-methyltransferase
  • catechol-O-methyltransferase 1
  • catecholamine-O-methyltransferase
  • catechol-O-methyltransferase
  • O-methyltransferase
  • catechol-o-methyltransferase
  • catechol O-methyltransferase, soluble form
  • catechol O-methyltransferase, membrane-bound form
  • catechol-O-methyltransferase a
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