CBFB Produkte
(Core-Binding Factor, beta Subunit (CBFB))
Kategorien
The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte CBFB Kategorien
CBFB Antikörper
High quality antibodies with extensive validation data.
CBFB Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CBFB Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7444325
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (5)
Kat. Nr.
ABIN390892
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6257985
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CBFB ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951394
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CBFB Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348166
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348164
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7417792
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CBFB Produkten
: "Functions of Smad Transcription Factors in TGF-β1-Induced Selectin Ligand Expression on Murine CD4 Th Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2627-34, (2016) (PubMed).Synonyme und alternative Namen zu CBFB
core-binding factor beta subunit (CBFB), core binding factor beta subunit (Cbfb), core-binding factor, beta subunit (cbfb), core-binding factor, beta subunit (Cbfb), core-binding factor, beta subunit S homeolog (cbfb.S), core binding factor beta (Cbfb), core-binding factor beta subunit (Cbfb), AI893578, cbf-beta, Cbfb, CBFB, cbfbeta, PEA2, pea2-beta, Pebp2, pebp2-beta, PEBP2B, pebp2b, PEBP2b, Pebpb2, unp1266Bezeichner auf Proteinebene für CBFB
- CBF-beta
- PEA2-beta
- PEBP2-beta
- SL3-3 enhancer factor 1 beta subunit
- SL3-3 enhancer factor 1 subunit beta
- SL3/AKV core-binding factor beta subunit
- core-binding factor subunit beta
- polyomavirus enhancer binding protein 2, beta subunit
- polyomavirus enhancer-binding protein 2 beta subunit
- core binding factor beta subunit
- core-binding factor, beta subunit
- core binding factor beta
- core-binding factor beta
- CCAAT-binding transcription factor subunit B
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