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CBFA2T2 Produkte

(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))

Kategorien

In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte CBFA2T2 Kategorien

CBFA2T2 Antikörper

High quality antibodies with extensive validation data.

CBFA2T2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CBFA2T2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN522603
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN522600
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN522599
Menge 50 μg
Datenblatt Datenblatt

Empfohlene CBFA2T2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348158
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348157
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3131988
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CBFA2T2 Produkten

Meier, Krpic, Rodriguez, Strouboulis, Monti, Krijgsveld, Gering, Patient, Hostert, Grosveld: "Novel binding partners of Ldb1 are required for haematopoietic development." in: Development (Cambridge, England), Vol. 133, Issue 24, pp. 4913-23, (2006) (PubMed).

Synonyme und alternative Namen zu CBFA2T2

CBFA2/RUNX1 translocation partner 2 (Cbfa2t2), CBFA2/RUNX1 translocation partner 2 (CBFA2T2), core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2), CBFA2/RUNX1 translocation partner 2 L homeolog (cbfa2t2.L), A430091M07, C330013D05Rik, cbfa2t2-a, Cbfa2t2h, EHT, MTGR1, p85, XETOR, ZMYND3

Bezeichner auf Proteinebene für CBFA2T2

  • translocated to, 2
  • myeloid translocation gene-related protein 1
  • protein CBFA2T2
  • CBFA2T2 identified gene homolog
  • MTG8-like protein
  • MTG8-related protein 1
  • core-binding factor runt domain alpha subunit 2 translocated to 2 homolog
  • core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog
  • ETO homolog on chromosome 20
  • ETO homologous on chromosome 20
  • myeloid translocation-related protein 1
  • a subunit 2; translocated to, 2
  • expressed during neurogenesis
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