Calmodulin 2 Protein (His tag)

Produktnummer ABIN7317378

Produktdetails

Target: Calmodulin 2 (Calm2) (Calmodulin 2 (phosphorylase Kinase, Delta) (Calm2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Calmodulin 2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Calmodulin 2/CALM2 Protein (His Tag)

Sequenz: Met 1-Lys149

Produktmerkmale: A DNA sequence encoding the mature form of human CALM2 (P0DP24) (Met1-Lys149) was expressed with a polyhistide tag at the N-terminus.

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Calmodulin 2 (Calm2) (Calmodulin 2 (phosphorylase Kinase, Delta) (Calm2))

Andere Bezeichnung: Calmodulin 2/CALM2 (Calm2 Produkte)

Synonyme: CAMII Protein, PHKD Protein, PHKD2 Protein, 1500001E21Rik Protein, AL024017 Protein, calm1 Protein, camii Protein, phkd Protein, phkd2 Protein, ATCAL5 Protein, CALMODULIN 2 Protein, T3K9.12 Protein, T3K9_12 Protein, calmodulin 2 Protein, CALM2 Protein, calmodulin 2 Protein, calmodulin 2 (phosphorylase kinase, delta) L homeolog Protein, calmodulin-like Protein, CALM2 Protein, Calm2 Protein, calm2.L Protein, CAM2 Protein, CALM Protein

Hintergrund:

Background: Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage.

Synonym: caM,CAMII,LQT15,PHKD,PHKD2

Molekulargewicht: 18.7 kDa

UniProt: P0DP24

Pathways: RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cellular Glucan Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Phototransduction, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals, BCR Signaling