CLEC5A Protein (His tag)
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- Target Alle CLEC5A Proteine anzeigen
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Protein-Typ
- Recombinant
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Spezies
- Ratte
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CLEC5A Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Rat CLEC5A/MDL1/MDL-1 Protein (His Tag)
- Sequenz
- Val30-Lys190
- Produktmerkmale
- A DNA sequence encoding the rat CLEC5A (F7GAV1) (Val30-Lys190) was expressed with a polyhistidine tag at the N-terminus.
- Reinheit
- > 95 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CLEC5A Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Andere Bezeichnung
- CLEC5A/MDL1/MDL-1 (CLEC5A Produkte)
- Synonyme
- CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
- Hintergrund
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Background: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
Synonym: CLEC5A
- Molekulargewicht
- 20.6 kDa
- UniProt
- F7GAV1
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