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CLEC5A Protein (His tag)

MALS verified CLEC5A Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN7121255
  • Target Alle CLEC5A Proteine anzeigen
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 3
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CLEC5A Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
    Sequenz
    Pro 28 - Lys 188
    Produktmerkmale
    Human CLEC5A, His Tag (CLA-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 28 - Lys 188 (Accession # Q9NY25-1).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Güteklasse
    MALS verified
    Top Product
    Discover our top product CLEC5A Protein
  • Applikationshinweise
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 60-66 kDa under reducing (R) condition due to glycosylation.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Andere Bezeichnung
    CLEC5A / MDL-1 (CLEC5A Produkte)
    Synonyme
    CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
    Hintergrund
    Synonyms: CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1,
    Description: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
    Molekulargewicht
    20.3 kDa
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