MASP2 Protein (Fc Tag)

Produktnummer ABIN7092694

Produktdetails

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MASP2 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human MASP2 protein with N-terminal Human Fc tag

Spezifität: HFc (Glu99-Ala330) MASP2 (Gln298-Ser684)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Andere Bezeichnung: MASP2 (MASP2 Produkte)

Synonyme: MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein

Hintergrund: Synonymes: MAP19, MASP-2, MASP1P1, sMAP
Description: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht: predicted molecular mass of 68.4 kDa after removal of the signal peptide.

Gen-ID: 10747

UniProt: O00187

Pathways: Komplementsystem