MASP2 Protein (AA 287-685) (His tag)
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- Target Alle MASP2 Proteine anzeigen
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 287-685
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses MASP2 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Mouse MASP2 Protein
- Sequenz
- Thr287-Phe685
- Produktmerkmale
- Recombinant Mouse MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MASP2 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl ( pH 9.0).
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- Andere Bezeichnung
- MASP2 (MASP2 Produkte)
- Synonyme
- MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein
- Hintergrund
- The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.
- Molekulargewicht
- 46.6 kDa. Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q91WP0
- Pathways
- Komplementsystem
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