Dieses SARS-CoV-2 Nucleocapsid Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS), ELISA
Verwendungszweck
SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron)
Produktmerkmale
SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1(P13L, ERS31-33del, R203K, G204R). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: B.1.1.529; GISAID clade: GR/484A; Nextstrain clade: 21K). Predicted N-terminus: Met 1
SARS-CoV-2 N
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Handhabung
Please avoid repeated freeze-thaw cycles.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at: 4-8°C for 12 months in lyophilized state, -70°C for 3 months under sterile conditions after reconstitution.
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.