Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (AA 1-419) (His-SUMOstar Tag)

SARS-CoV-2 N Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: Hefe Recombinant Greater than 90 % as determined by SDS-PAGE.
Produktnummer ABIN6953162
  • Target Alle SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Proteine anzeigen
    SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-419
    Spezies
    • 53
    • 6
    • 5
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Quelle
    • 29
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Hefe
    Aufreinigungstag / Konjugat
    Dieses SARS-CoV-2 Nucleocapsid Protein ist gelabelt mit His-SUMOstar Tag.
    Sequenz
    MSDNGPQNQR NAPRITFGGP SDSTGSNQNG ERSGARSKQR RPQGLPNNTA SWFTALTQHG KEDLKFPRGQ GVPINTNSSP DDQIGYYRRA TRRIRGGDGK MKDLSPRWYF YYLGTGPEAG LPYGANKDGI IWVATEGALN TPKDHIGTRN PANNAAIVLQ LPQGTTLPKG FYAEGSRGGS QASSRSSSRS RNSSRNSTPG SSRGTSPARM AGNGGDAALA LLLLDRLNQL ESKMSGKGQQ QQGQTVTKKS AAEAS
    Produktmerkmale
    N-terminal 6xHis-sumostar-tagged
    Reinheit
    Greater than 90 % as determined by SDS-PAGE.
    Top Product
    Discover our top product SARS-CoV-2 N Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50 % of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C.
    Buffer
    Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6 % Trehalose, pH 8.0
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • Target
    SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
    Andere Bezeichnung
    SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N Produkte)
    Synonyme
    nucleocapsid phosphoprotein Protein, N Protein
    Substanzklasse
    Viral Protein
    Hintergrund
    Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Coronavirus nucleoproteins are phosphoproteins, and are encoded near the 3' end of the genome. N possesses two RNA-binding domains: an N-terminal domain with adjacent S/R-rich motif and the C-terminal 209 amino acids. N protein is invovled in coronavirus infection with many ways: the C-terminal domain (CTD) of N is important for binding the genomic RNA packaging signal leading to selective genome incorporation, the N3 domain interacts with the endodomain of M to form virions, and the serine-arginine repeat region of N (SR) interacts with the first ubiquitin-like domain of nsp3 in a critical early replication step. Moreover, it has also been demonstrated that N can oligomerize through interactions in the CTD, bind viral RNA through the N-terminal domain, unwind double-stranded nucleic acid in the manner of an RNA chaperone, and pack in a helix through the N-terminal domain, though none of these other functions has yet been demonstrated to be important for infection.
    Molekulargewicht
    67.6 kDa
    UniProt
    P0DTC9
Sie sind hier:
Kundenservice