IL-8 Protein (AA 28-99) (Fc Tag)
-
- Target Alle IL-8 (IL8) Proteine anzeigen
- IL-8 (IL8) (Interleukin 8 (IL8))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 28-99
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL-8 Protein ist gelabelt mit Fc Tag.
- Produktmerkmale
- Human IL-8 / CXCL8 Protein, Fc Tag
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL8 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
- Lagerung
- -20 °C
-
- Target
- IL-8 (IL8) (Interleukin 8 (IL8))
- Andere Bezeichnung
- IL-8 (IL8 Produkte)
- Synonyme
- CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
- Hintergrund
- Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
- Molekulargewicht
- 34.8 kDa
- NCBI Accession
- NP_000575
- Pathways
- TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
-