SARS-CoV-2 Spike Protein (P.1 - gamma) (His tag)
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- Target Alle SARS-CoV-2 Spike Proteine anzeigen
- SARS-CoV-2 Spike
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- P.1 - gamma
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Spezies
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SARS-CoV-2 Spike Protein ist gelabelt mit His tag.
- Sequenz
- AA 319-537
- Spezifität
- SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (MALS verified)
- Produktmerkmale
- SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1(K417T, E484K, N501Y). K417T/ E484K/ N501Y mutations were identified in the SARS-CoV-2 variant (known as variant P.1) which emerged in Brazil.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike Protein
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- Applikationshinweise
- MALS verified
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- SARS-CoV-2 Spike
- Andere Bezeichnung
- SARS-CoV-2 S protein (SARS-CoV-2 Spike Produkte)
- Synonyme
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molekulargewicht
- 26.5 kDa
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