SARS-CoV-2 Spike Protein (B.1.621 - mu) (rho-1D4 tag)

Produktnummer ABIN7013133

Produktdetails

Highlights:

• Recombinant trimeric S protein of the SARS-CoV-2 variant of interest B.1.621 mu.
• Contains T95I, Y144S, Y145N, R346K, E484K, N501Y, D614G, P681H and D950N mutations characteristic for the SARS-CoV-2 mu variant (B.1.621).

Target: SARS-CoV-2 Spike

Protein-Typ: Recombinant

Proteineigenschaft: B.1.621 - mu

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Mu

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike Protein ist gelabelt mit rho-1D4 tag.

Applikation: ELISA, Ligand Binding Assay (LBA)

Verwendungszweck: This is the spike protein of the mutant strain B.1.621 (WHO variant of concern Mu).

Spezifität: Mutations that differ from "original" SPIKE protein: T95I, Y144S, Y145N, R346K, N501Y, D614G, P681H, D950N

Produktmerkmale: All viruses undergo fast mutations to adept quickly to the host's immune response and boost infectivity. SARS-CoV-2, the causative agent of COVID-19, is no exception. Over the course of the COVID-19 pandemic several predominant novel strains have already been identified. The B.1.621 Mu variant was first detected in Colombia in January 2021 and was added to the WHO list of SARS-CoV-2 variants of interest in August 2021.

Aufreinigung: affinity chromatography

Reinheit: > 98% as determined by SDS-PAGE

Anwendungsinformationen

Kommentare:

Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1284 amino acids (including Rho1D4 tag and linker) 141903 Da

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Avoid freeze-thaw cycles

Antigendetails

Target: SARS-CoV-2 Spike

Andere Bezeichnung: SARS2 Spike glycoprotein (SARS-CoV-2 Spike Produkte)

Synonyme: E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein

Substanzklasse: Viral Protein

UniProt: P0DTC2