SARS-CoV-2 Spike S1 Protein (B.1.351 - beta) (Fc Tag)

Produktnummer ABIN6992404

Produktdetails

Target: SARS-CoV-2 Spike S1

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: B.1.351 - beta

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike S1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: SARS-CoV-2 S1 protein (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G), Fc Tag

Sequenz: AA 16-685

Produktmerkmale: SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G) were identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in the South Africa.

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Lagerung: -20 °C

Antigendetails

Target: SARS-CoV-2 Spike S1

Andere Bezeichnung: SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Produkte)

Synonyme: E2 Protein, Surface Glycoprotein Protein, S Protein

Substanzklasse: Viral Protein

Hintergrund: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molekulargewicht: 101.1 kDa