SARS-CoV-2 Spike S1 Protein (E484K, K417N, N501Y) (His tag)
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- Target Alle SARS-CoV-2 Spike S1 Proteine anzeigen
- SARS-CoV-2 Spike S1
- Protein-Typ
- Recombinant
- Proteineigenschaft
- E484K, K417N, N501Y
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Spezies
- SARS Coronavirus-2 (SARS-CoV-2)
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SARS-CoV-2 Spike S1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- SARS-COV-2 Spike S1 (N501Y,K417N,E484K) Protein
- Sequenz
- Val16-Arg685 (N501Y,K417N,E484K)
- Produktmerkmale
- Recombinant SARS-COV-2 Spike S1 (N501Y,K417N,E484K) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val16-Arg685(N501Y,K417N,E484K).
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized SARS-COV-2 Spike S1 (N501Y,K417N,E484K) , His Tag at 0.5μg/ml (100ul/Well) on the plate. Dose response curve for Human ACE2, hFc Tag with the EC50 of 0.02μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SARS-CoV-2 Spike S1
- Abstract
- SARS-CoV-2 Spike S1 Produkte
- Synonyme
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molekulargewicht
- 75.9 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- YP_009724390
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