SARS-CoV-2 Spike S1 Protein (B.1.351 - beta) (His tag)
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- Target Alle SARS-CoV-2 Spike S1 Proteine anzeigen
- SARS-CoV-2 Spike S1
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- B.1.351 - beta
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Spezies
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SARS-CoV-2 Spike S1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- SARS-CoV-2 S1 protein NTD (L18F, D80A, D215G, 242-244del, R246I), His Tag (MALS verified)
- Sequenz
- AA 13-303
- Produktmerkmale
- SARS-CoV-2 S1 protein NTD, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The L18F/D80A/D215G/LAL242-244del/R246I mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in South Africa.
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- SARS-CoV-2 Spike S1
- Andere Bezeichnung
- SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Produkte)
- Synonyme
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molekulargewicht
- 34.5 kDa
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