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IL11RA Protein (AA 24-370) (Fc Tag)

IL11RA Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6992343
  • Target Alle IL11RA Proteine anzeigen
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-370
    Spezies
    • 10
    • 5
    • 1
    Human
    Quelle
    • 6
    • 5
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL11RA Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Human IL-11 R alpha Protein, Fc Tag (MALS verified)
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL11RA Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
  • Target
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Andere Bezeichnung
    IL-11 R alpha (IL11RA Produkte)
    Synonyme
    CRSDA Protein, fi26e06 Protein, il-11ra Protein, wu:fi26e06 Protein, AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor subunit alpha Protein, interleukin 11 receptor, alpha Protein, interleukin 11 receptor subunit alpha 1 Protein, interleukin 11 receptor, alpha chain 1 Protein, IL11RA Protein, il11ra Protein, Il11ra1 Protein, Il11ra Protein
    Hintergrund
    Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
    Molekulargewicht
    64.3 kDa
    NCBI Accession
    NP_001136256
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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