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NOTCH3 Protein (AA 40-467) (Fc Tag)

NOTCH3 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN6992329
  • Target Alle NOTCH3 Proteine anzeigen
    NOTCH3 (Notch 3 (NOTCH3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 40-467
    Spezies
    • 12
    • 5
    Human
    Quelle
    • 8
    • 5
    • 3
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses NOTCH3 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Human NOTCH3 Protein, Fc Tag
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NOTCH3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    Lagerung
    -20 °C
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Andere Bezeichnung
    NOTCH3 (NOTCH3 Produkte)
    Synonyme
    CADASIL Protein, CASIL Protein, IMF2 Protein, AW229011 Protein, N3 Protein, hpbk Protein, fa14b08 Protein, notch5 Protein, wu:fa14b08 Protein, notch 3 Protein, NOTCH3 Protein, Notch3 Protein, notch3 Protein
    Hintergrund
    Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs
    Molekulargewicht
    71.4 kDa
    NCBI Accession
    NP_000426
    Pathways
    Notch Signalweg
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