NOTCH3 Produkte
(Notch 3 (NOTCH3))
Kategorien
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].
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Ausgewählte NOTCH3 Kategorien
NOTCH3 Antikörper
High quality antibodies with extensive validation data.
NOTCH3 ELISA Kits
Reliable ELISA kits for a wide range of species.
NOTCH3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NOTCH3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7074862
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IF, IHC (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN390159
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN3023484
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NOTCH3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968971
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968972
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958226
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NOTCH3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275361
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275366
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275362
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NOTCH3 Produkten
: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." in: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).
: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).
: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).
: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." in: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).
: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." in: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).
: "Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis." in: Neurobiology of disease, Vol. 75, pp. 131-41, (2015) (PubMed).
: "Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord." in: Journal of cellular and molecular medicine, Vol. 18, Issue 10, pp. 2103-16, (2014) (PubMed).
: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).
: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
Synonyme und alternative Namen zu NOTCH3
notch 3 (NOTCH3), notch 3 (Notch3), notch 3 (notch3), AW229011, CADASIL, CASIL, fa14b08, hpbk, IMF2, N3, notch5, wu:fa14b08Bezeichner auf Proteinebene für NOTCH3
- Notch homolog 3
- neurogenic locus notch homolog protein 3
- Notch gene homolog 3
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