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LRP6 Protein (AA 20-630) (Fc Tag)

LRP6 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6938849
  • Target Alle LRP6 Proteine anzeigen
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 20-630
    Spezies
    • 7
    • 3
    Human
    Quelle
    • 6
    • 3
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses LRP6 Protein ist gelabelt mit Fc Tag.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product LRP6 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Lagerung
    -20 °C
  • Target
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    Andere Bezeichnung
    LRP-6 (LRP6 Produkte)
    Synonyme
    lrp6-A Protein, Xlrp6 Protein, adcad2 Protein, lrp6 Protein, LRP6 Protein, ADCAD2 Protein, C030016K15Rik Protein, Cd Protein, Gw Protein, LDL receptor related protein 6 Protein, LDL receptor related protein 6 L homeolog Protein, LDL receptor related protein 6 S homeolog Protein, low density lipoprotein receptor-related protein 6 Protein, low-density lipoprotein receptor-related protein 6 Protein, LRP6 Protein, lrp6.L Protein, lrp6.S Protein, lrp6 Protein, Lrp6 Protein, LOC590395 Protein
    Hintergrund
    LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
    Molekulargewicht
    95.8 kDa
    NCBI Accession
    NP_002327
    Pathways
    WNT Signalweg, Tube Formation
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