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LRP6 Produkte

(Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

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Ausgewählte LRP6 Kategorien

LRP6 Antikörper

High quality antibodies with extensive validation data.

LRP6 ELISA Kits

Reliable ELISA kits for a wide range of species.

LRP6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene LRP6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IHC, WB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN6263009
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (p), WB
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN390100
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, ELISA, WB
Validierungen
  • (3)
Kat. Nr. ABIN3028807
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene LRP6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6957542
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6973692
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968356
Menge 96 tests
Datenblatt Datenblatt

Empfohlene LRP6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN6938849
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3093578
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3132151
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren LRP6 Produkten

Priestley, Cheung, Murphy, Ehebauer, Davis, Di Daniel: "A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6." in: Journal of pharmacological and toxicological methods, Vol. 95, pp. 47-55, (2019) (PubMed).

Du, Wang, Ye, He, Li, Du, Liu, Zhu: "Exercise training ameliorates bleomycin-induced epithelial mesenchymal transition and lung fibrosis through restoration of H2 S synthesis." in: Acta physiologica (Oxford, England), pp. e13177, (2018) (PubMed).

Duvetorp, Olsen, Nyström, Skarstedt, Dienus, Mrowietz, Söderman, Seifert: "Expression of low-density lipoprotein-related receptors 5 and 6 (LRP5/6) in psoriasis skin." in: Experimental dermatology, Vol. 26, Issue 11, pp. 1033-1038, (2018) (PubMed).

Xiao, Fei, Hurley: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." in: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).

Zhu, Wang, Zhao, Zhang, Wu, Wang, Hu: "Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma." in: Oncotarget, Vol. 8, Issue 14, pp. 22825-22834, (2017) (PubMed).

Boone, Arend, Johnston, Cooper, Gilchrist, Oelschlager, Grizzle, McGwin, Gangrade, Straughn, Buchsbaum: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, (2016) (PubMed).

Madan, Walker, Young, Quick, Orgel, Ryan, Gupta, Henrich, Ferrer, Marine, Roberts, Arthur, Berndt, Oliveira, Moon, Virshup, Chou, Major: "USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. E2945-54, (2016) (PubMed).

Goetzl, Boxer, Schwartz, Abner, Petersen, Miller, Carlson, Mustapic, Kapogiannis: "Low neural exosomal levels of cellular survival factors in Alzheimer's disease." in: Annals of clinical and translational neurology, Vol. 2, Issue 7, pp. 769-73, (2015) (PubMed).

Lemieux, Cagnol, Beaudry, Carrier, Rivard: "Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer." in: Oncogene, Vol. 34, Issue 38, pp. 4914-27, (2015) (PubMed).

Chen, Xu, Ye, Li, Gong, Zhang, Wu, Jia, Liu, Chen, Yang, Tang, Zhu, Ge, Zou: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, (2014) (PubMed).

Synonyme und alternative Namen zu LRP6

LDL receptor related protein 6 (LRP6), LDL receptor related protein 6 L homeolog (lrp6.L), LDL receptor related protein 6 S homeolog (lrp6.S), low density lipoprotein receptor-related protein 6 (lrp6), LDL receptor related protein 6 (lrp6), low density lipoprotein receptor-related protein 6 (Lrp6), LDL receptor related protein 6 (Lrp6), low-density lipoprotein receptor-related protein 6 (LOC590395), adcad2, ADCAD2, C030016K15Rik, Cd, Gw, lrp6, LRP6, lrp6-A, Xlrp6

Bezeichner auf Proteinebene für LRP6

  • low density lipoprotein receptor-related protein 6
  • lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6-like
  • LRP-6
  • crooked
  • low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6
  • low density lipoprotein-related protein 6
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