LRP6 Produkte
(Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
Kategorien
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
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Ausgewählte LRP6 Kategorien
LRP6 Antikörper
High quality antibodies with extensive validation data.
LRP6 ELISA Kits
Reliable ELISA kits for a wide range of species.
LRP6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LRP6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC, Neut
Validierungen
- (4)
Kat. Nr.
ABIN7193277
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN390100
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Human, Mouse, Rat
Applikation
WB, ELISA, IP, DB
Validierungen
- (4)
- (2)
Kat. Nr.
ABIN540939
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene LRP6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957542
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6973692
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968357
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LRP6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275210
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN6938849
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3093578
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LRP6 Produkten
: "A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6." in: Journal of pharmacological and toxicological methods, Vol. 95, pp. 47-55, (2019) (PubMed).: "Exercise training ameliorates bleomycin-induced epithelial mesenchymal transition and lung fibrosis through restoration of H2 S synthesis." in: Acta physiologica (Oxford, England), pp. e13177, (2018) (PubMed).
: "Expression of low-density lipoprotein-related receptors 5 and 6 (LRP5/6) in psoriasis skin." in: Experimental dermatology, Vol. 26, Issue 11, pp. 1033-1038, (2018) (PubMed).
: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." in: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).
: "Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma." in: Oncotarget, Vol. 8, Issue 14, pp. 22825-22834, (2017) (PubMed).
: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, (2016) (PubMed).
: "USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. E2945-54, (2016) (PubMed).
: "Low neural exosomal levels of cellular survival factors in Alzheimer's disease." in: Annals of clinical and translational neurology, Vol. 2, Issue 7, pp. 769-73, (2015) (PubMed).
: "Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer." in: Oncogene, Vol. 34, Issue 38, pp. 4914-27, (2015) (PubMed).
: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, (2014) (PubMed).
Synonyme und alternative Namen zu LRP6
LDL receptor related protein 6 (LRP6), LDL receptor related protein 6 L homeolog (lrp6.L), LDL receptor related protein 6 S homeolog (lrp6.S), low density lipoprotein receptor-related protein 6 (lrp6), LDL receptor related protein 6 (lrp6), low density lipoprotein receptor-related protein 6 (Lrp6), LDL receptor related protein 6 (Lrp6), low-density lipoprotein receptor-related protein 6 (LOC590395), adcad2, ADCAD2, C030016K15Rik, Cd, Gw, lrp6, LRP6, lrp6-A, Xlrp6Bezeichner auf Proteinebene für LRP6
- low density lipoprotein receptor-related protein 6
- lipoprotein receptor-related protein 6
- low-density lipoprotein receptor-related protein 6
- low-density lipoprotein receptor-related protein 6-like
- LRP-6
- crooked
- low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6
- low density lipoprotein-related protein 6
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