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IL12RB1 Protein (AA 24-540) (His tag)

IL12RB1 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6809932
  • Target Alle IL12RB1 Proteine anzeigen
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-540
    Spezies
    • 13
    • 5
    • 1
    Human
    Quelle
    • 9
    • 4
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL12RB1 Protein ist gelabelt mit His tag.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL12RB1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
  • Target
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Andere Bezeichnung
    IL-12 R beta 1 (IL12RB1 Produkte)
    Synonyme
    Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
    Hintergrund
    The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
    Molekulargewicht
    59.0 kDa
    NCBI Accession
    NP_005526
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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