IL12RB1 Protein (AA 24-540) (Fc Tag)
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- Target Alle IL12RB1 Proteine anzeigen
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 24-540
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL12RB1 Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 24-540
- Reinheit
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL12RB1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- Andere Bezeichnung
- IL-12 R beta 1 (IL12RB1 Produkte)
- Synonyme
- Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
- Hintergrund
- The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
- Molekulargewicht
- 83.5 kDa
- NCBI Accession
- NP_005526
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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