NFKBIB Protein (AA 1-356) (His tag)

Produktnummer ABIN667688

Produktdetails

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-356

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NFKBIB Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: NFKBIB, 1-356aa , Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Andere Bezeichnung: NFKBIB (NFKBIB Produkte)

Synonyme: NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein

Hintergrund: NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: IKBB, TRIP9. NCBI no.: NP_002494

Molekulargewicht: 40.3 kDa (380aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades