BIN1 Protein (AA 1-439) (His tag)

Produktnummer ABIN667182

Produktdetails

Target: BIN1 (Bridging Integrator 1 (BIN1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-439

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BIN1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: BIN1, 1-439aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS – PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: BIN1 (Bridging Integrator 1 (BIN1))

Andere Bezeichnung: BIN1 (BIN1 Produkte)

Synonyme: bin1 Protein, MGC53185 Protein, amph2 Protein, amphl Protein, sh3p9 Protein, MGC76187 Protein, cb57 Protein, zgc:86701 Protein, BIN1 Protein, AMPH2 Protein, AMPHL Protein, SH3P9 Protein, ALP-1 Protein, Amphl Protein, BRAMP-2 Protein, bridging integrator 1 Protein, bridging integrator 1 S homeolog Protein, bridging integrator 1b Protein, BIN1 Protein, bin1.S Protein, bin1 Protein, bin1b Protein, Bin1 Protein

Hintergrund: BIN1, also known as SH3P9, is a nucleocytoplasmic adaptor protein, one of which was initially identified as MYC-interacting protein with features of a tumor suppressor. This protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Recombinant human BIN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AMPH2, AMPHL, MGC10367, SH3P9, Amphiphysin II, Myc box-dependent-interacting protein 1. NCBI no.: AAH04101

Molekulargewicht: 50.4 kDa (459aa) confirmed by MALDI-TOF